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rabbit polyclonal anti cd8α  (Bioss)


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    Structured Review

    Bioss rabbit polyclonal anti cd8α
    ( A–E ) The male Oxt Cre mice (2 months of age) were injected with the indicated adeno-associated viruses (AAVs) into the paraventricular nucleus (PVN), and were then treated with azoxymethane (AOM) and dextran sodium sulfate (DSS). Thereafter, clozapine-N-oxide (CNO) was i.p. injected every other day for 3 weeks. Immunohistochemical stainings for <t>CD8α,</t> CD4, B220, NK1.1, and CD11b of tumor tissue sections were carried out. Representative images are shown. Scale bars, 50 μm. ( F–J ) The density of immune cells in tumor tissue. n = 4 (control, B220 or control, NK1.1) or 5 (all other groups) mice per group. Data are presented as mean ± SEM. *p < 0.05, two-tailed Student’s t-test ( F ).
    Rabbit Polyclonal Anti Cd8α, supplied by Bioss, used in various techniques. Bioz Stars score: 95/100, based on 108 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit polyclonal anti cd8α/product/Bioss
    Average 95 stars, based on 108 article reviews
    rabbit polyclonal anti cd8α - by Bioz Stars, 2026-06
    95/100 stars

    Images

    1) Product Images from "Stimulation of hypothalamic oxytocin neurons suppresses colorectal cancer progression in mice"

    Article Title: Stimulation of hypothalamic oxytocin neurons suppresses colorectal cancer progression in mice

    Journal: eLife

    doi: 10.7554/eLife.67535

    ( A–E ) The male Oxt Cre mice (2 months of age) were injected with the indicated adeno-associated viruses (AAVs) into the paraventricular nucleus (PVN), and were then treated with azoxymethane (AOM) and dextran sodium sulfate (DSS). Thereafter, clozapine-N-oxide (CNO) was i.p. injected every other day for 3 weeks. Immunohistochemical stainings for CD8α, CD4, B220, NK1.1, and CD11b of tumor tissue sections were carried out. Representative images are shown. Scale bars, 50 μm. ( F–J ) The density of immune cells in tumor tissue. n = 4 (control, B220 or control, NK1.1) or 5 (all other groups) mice per group. Data are presented as mean ± SEM. *p < 0.05, two-tailed Student’s t-test ( F ).
    Figure Legend Snippet: ( A–E ) The male Oxt Cre mice (2 months of age) were injected with the indicated adeno-associated viruses (AAVs) into the paraventricular nucleus (PVN), and were then treated with azoxymethane (AOM) and dextran sodium sulfate (DSS). Thereafter, clozapine-N-oxide (CNO) was i.p. injected every other day for 3 weeks. Immunohistochemical stainings for CD8α, CD4, B220, NK1.1, and CD11b of tumor tissue sections were carried out. Representative images are shown. Scale bars, 50 μm. ( F–J ) The density of immune cells in tumor tissue. n = 4 (control, B220 or control, NK1.1) or 5 (all other groups) mice per group. Data are presented as mean ± SEM. *p < 0.05, two-tailed Student’s t-test ( F ).

    Techniques Used: Injection, Immunohistochemical staining, Two Tailed Test


    Figure Legend Snippet:

    Techniques Used: Enzyme-linked Immunosorbent Assay, In Situ, Software



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    Bioss rabbit polyclonal anti cd8α
    ( A–E ) The male Oxt Cre mice (2 months of age) were injected with the indicated adeno-associated viruses (AAVs) into the paraventricular nucleus (PVN), and were then treated with azoxymethane (AOM) and dextran sodium sulfate (DSS). Thereafter, clozapine-N-oxide (CNO) was i.p. injected every other day for 3 weeks. Immunohistochemical stainings for <t>CD8α,</t> CD4, B220, NK1.1, and CD11b of tumor tissue sections were carried out. Representative images are shown. Scale bars, 50 μm. ( F–J ) The density of immune cells in tumor tissue. n = 4 (control, B220 or control, NK1.1) or 5 (all other groups) mice per group. Data are presented as mean ± SEM. *p < 0.05, two-tailed Student’s t-test ( F ).
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    ( A–E ) The male Oxt Cre mice (2 months of age) were injected with the indicated adeno-associated viruses (AAVs) into the paraventricular nucleus (PVN), and were then treated with azoxymethane (AOM) and dextran sodium sulfate (DSS). Thereafter, clozapine-N-oxide (CNO) was i.p. injected every other day for 3 weeks. Immunohistochemical stainings for <t>CD8α,</t> CD4, B220, NK1.1, and CD11b of tumor tissue sections were carried out. Representative images are shown. Scale bars, 50 μm. ( F–J ) The density of immune cells in tumor tissue. n = 4 (control, B220 or control, NK1.1) or 5 (all other groups) mice per group. Data are presented as mean ± SEM. *p < 0.05, two-tailed Student’s t-test ( F ).
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    The therapeutic effect of MFTA in vivo . (A) Schematic illustration of the experimental design in vivo . (B) Body weight assessments in various treatment groups. (C) Tumor weight. (D) Relative tumor volume. (E) Images of dissected tumors. (F) H&E, Ki67 protein, TUNEL, <t>CD8</t> and HMGB-1 staining images in tumor tissues after different treatments. CD8 (G) and HMGB-1(H) images from immunofluorescence were quantified with Image J. **** p < 0.0001.
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    The therapeutic effect of MFTA in vivo . (A) Schematic illustration of the experimental design in vivo . (B) Body weight assessments in various treatment groups. (C) Tumor weight. (D) Relative tumor volume. (E) Images of dissected tumors. (F) H&E, Ki67 protein, TUNEL, <t>CD8</t> and HMGB-1 staining images in tumor tissues after different treatments. CD8 (G) and HMGB-1(H) images from immunofluorescence were quantified with Image J. **** p < 0.0001.
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    Image Search Results


    ( A–E ) The male Oxt Cre mice (2 months of age) were injected with the indicated adeno-associated viruses (AAVs) into the paraventricular nucleus (PVN), and were then treated with azoxymethane (AOM) and dextran sodium sulfate (DSS). Thereafter, clozapine-N-oxide (CNO) was i.p. injected every other day for 3 weeks. Immunohistochemical stainings for CD8α, CD4, B220, NK1.1, and CD11b of tumor tissue sections were carried out. Representative images are shown. Scale bars, 50 μm. ( F–J ) The density of immune cells in tumor tissue. n = 4 (control, B220 or control, NK1.1) or 5 (all other groups) mice per group. Data are presented as mean ± SEM. *p < 0.05, two-tailed Student’s t-test ( F ).

    Journal: eLife

    Article Title: Stimulation of hypothalamic oxytocin neurons suppresses colorectal cancer progression in mice

    doi: 10.7554/eLife.67535

    Figure Lengend Snippet: ( A–E ) The male Oxt Cre mice (2 months of age) were injected with the indicated adeno-associated viruses (AAVs) into the paraventricular nucleus (PVN), and were then treated with azoxymethane (AOM) and dextran sodium sulfate (DSS). Thereafter, clozapine-N-oxide (CNO) was i.p. injected every other day for 3 weeks. Immunohistochemical stainings for CD8α, CD4, B220, NK1.1, and CD11b of tumor tissue sections were carried out. Representative images are shown. Scale bars, 50 μm. ( F–J ) The density of immune cells in tumor tissue. n = 4 (control, B220 or control, NK1.1) or 5 (all other groups) mice per group. Data are presented as mean ± SEM. *p < 0.05, two-tailed Student’s t-test ( F ).

    Article Snippet: Antibody , (Rabbit polyclonal) anti-CD8α , Bioss , Cat# bs-0648R; RRID: AB_10857537 , IHC, (1:250).

    Techniques: Injection, Immunohistochemical staining, Two Tailed Test

    Journal: eLife

    Article Title: Stimulation of hypothalamic oxytocin neurons suppresses colorectal cancer progression in mice

    doi: 10.7554/eLife.67535

    Figure Lengend Snippet:

    Article Snippet: Antibody , (Rabbit polyclonal) anti-CD8α , Bioss , Cat# bs-0648R; RRID: AB_10857537 , IHC, (1:250).

    Techniques: Enzyme-linked Immunosorbent Assay, In Situ, Software

    The therapeutic effect of MFTA in vivo . (A) Schematic illustration of the experimental design in vivo . (B) Body weight assessments in various treatment groups. (C) Tumor weight. (D) Relative tumor volume. (E) Images of dissected tumors. (F) H&E, Ki67 protein, TUNEL, CD8 and HMGB-1 staining images in tumor tissues after different treatments. CD8 (G) and HMGB-1(H) images from immunofluorescence were quantified with Image J. **** p < 0.0001.

    Journal: RSC Advances

    Article Title: Novel self-assembled metal-phenolic nanoplatforms for triple-negative breast cancer treatment: photothermal-chemotherapy/ferroptosis synergy inducing immunogenic cell death

    doi: 10.1039/d5ra03962b

    Figure Lengend Snippet: The therapeutic effect of MFTA in vivo . (A) Schematic illustration of the experimental design in vivo . (B) Body weight assessments in various treatment groups. (C) Tumor weight. (D) Relative tumor volume. (E) Images of dissected tumors. (F) H&E, Ki67 protein, TUNEL, CD8 and HMGB-1 staining images in tumor tissues after different treatments. CD8 (G) and HMGB-1(H) images from immunofluorescence were quantified with Image J. **** p < 0.0001.

    Article Snippet: Anti-calreticulin (CRT), anti-high-mobility group protein 1 (HMGB-1), and anti-CD8α rabbit polyclonal antibodies were procured from the Servicebio Technology.

    Techniques: In Vivo, TUNEL Assay, Staining, Immunofluorescence

    Evaluation of MFTA-induced specific anti-tumor immunity in vivo . (A) FCM analysis of CD8+ T cell populations in spleens. (B) FCM assessment of DC maturation in tumors following various treatments. (C) FCM analysis of DC maturation in regional lymph nodes after different treatments. (D) Quantitative analysis of splenic CD8+ T cell frequencies. (E) Statistical quantification of tumor-infiltrating DC maturation. (F) Quantitative assessment of DC maturation in lymph nodes. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.

    Journal: RSC Advances

    Article Title: Novel self-assembled metal-phenolic nanoplatforms for triple-negative breast cancer treatment: photothermal-chemotherapy/ferroptosis synergy inducing immunogenic cell death

    doi: 10.1039/d5ra03962b

    Figure Lengend Snippet: Evaluation of MFTA-induced specific anti-tumor immunity in vivo . (A) FCM analysis of CD8+ T cell populations in spleens. (B) FCM assessment of DC maturation in tumors following various treatments. (C) FCM analysis of DC maturation in regional lymph nodes after different treatments. (D) Quantitative analysis of splenic CD8+ T cell frequencies. (E) Statistical quantification of tumor-infiltrating DC maturation. (F) Quantitative assessment of DC maturation in lymph nodes. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.

    Article Snippet: Anti-calreticulin (CRT), anti-high-mobility group protein 1 (HMGB-1), and anti-CD8α rabbit polyclonal antibodies were procured from the Servicebio Technology.

    Techniques: In Vivo